Login / Register
0

Vardenafil HCl Trihydrate

Vardenafil HCl Trihydrate

Catalog Number:
L002369125APE
Mfr. No.:
APE-A4323
Price:
$223
  • Size:
    Quantity:
    Add to Cart:
    Add to Cart
      • Overview

        • Please contact us at for specific academic pricing.

          Background

          Vardenafil is a potent and selective inhibitor of phosphodiesterase type5 (PDE5) with the IC50 value of 0.7 nM in enzymatic assay in vitro [1]. Vardenafil HCl Trihydrate is a salt form of vardenafil. [1] Vardenafil has shown a greater selective inhibition towards PDE5 than PDEs from bovine, with the IC50 values of 180nM,>10000nM, 2500nM, 4000nM and 11nM for PDE1, PDE2, PDE3, PDE4 and PDE6, respectively. Besides, Vardenafil has been reported to significantly enhance the SNP-induced, ACh-induced and transmural electrical stimulation-induced relaxation of human trabecular smooth muscle. Vardenafil has been revealed to increase the amount of cGMP in human corpus cavernosum. Apart from these, Vardenafil has also enhanced the length of penile in the conscious rabbit [1].

      • Properties
        • Alternative Name
          2-[2-ethoxy-5-(4-ethylpiperazin-1-yl)sulfonylphenyl]-5-methyl-7-propyl-1H-imidazo[5,1-f][1,2,4]triazin-4-one
          CAS Number
          330808-88-3
          Molecular Formula
          C23H32N6O4S·HCl·3H2O
          Molecular Weight
          579.11
          Appearance
          A solid
          Purity
          99.63%
          Solubility
          ≥13.3 mg/mL in DMSO; ≥3.42 mg/mL in EtOH with gentle warming and ultrasonic; ≥95 mg/mL in H2O
          Storage
          Store at -20°C

          * For Research Use Only

    We Also Recommend

    PF-2545920

    PF-2545920

    $436

    Pioglitazone HCl

    Pioglitazone HCl

    $180

    TAK-700 (Orteronel)

    TAK-700 (Orteronel)

    $283

    Note: If you don't receive our verification email, do the following:

    Products
    Amerigo Scientific
    Support
    Contact Us
    Copyright © Amerigo Scientific. All rights reserved.