Urotensin II, human

Urotensin II, human

MW: 1387.2
H-Glu-Thr-Pro-Asp-Cys-Phe-Trp-Lys-Tyr-Cys-Val-OH (Cys5-10, cyclic)
Urotensin II is located in human vascular and cardiac tissue. It is the most potent vasoconstrictor known at the present time (1999), being an order of magnitude more potent than endothelin-1. Immunoreactivity has also been observed in CNS and endocrine tissues. A human orphan receptor for urotensin II has been described.
Coulouarn Y. et al. (1998) Proc. Soc. Acad. Sci. USA 95, 15803; Ames R.S. et al.(1999) Nature 401, 282.
1mg
5mg

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