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UMI-77

UMI-77

Catalog Number:

I002097347UBP

Mfr. No.:

F7150

Price:

$260

Size:

5 mg

Quantity:

Add to Cart:

- Overview
  - UMI-77 is a selective Mcl-1 inhibitor by binding of the BH3-binding groove of Mcl-1, by which it blocks the interactions of Bax/Mcl-1 and Bak/Mcl-1. UMI-77 inhibits growth of pancreatic cancer cells with IC50 of 3.4, 4.4, 12.5, 16.1, and 5.5 μM for BxPC-3, Panc-1, MiaPaCa-2, AsPC-1 and Capan-2 cells, respectively. UMI-77 induces apoptosis of various pancreatic cancer cell lines.
    
    Please contact us at for specific academic pricing.
- Properties
  - Protein Name
    
    2-[[4-[[(4-bromophenyl)sulfonyl]amino]-1-hydroxy-2-naphthalenyl]thio]-acetic acid
    
    Source
    
    Synthetic
    
    Formulation
    
    C18H14BrNO5S2
    
    Storage
    
    Eligible for room temperature shipping. Store at -20°C upon receiving; protect from air and light
    
    Molecular Weight
    
    468.34 g/mol
    
    * Research Use Only

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