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Overview
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Background
Act as a convergence point for multiple signals that control autophagy, and can bind to several autophagy-related (Atg) proteins, regulating phosphorylation states and protein trafficking. AMPK, activated during low nutrient conditions, directly phosphorylates ULK1 at multiple sites including Ser317, Ser555, and Ser777. Conversely, mTOR, which is a regulator of cell growth and an inhibitor of autophagy, phosphorylates ULK1 at Ser757 and disrupts the interaction between ULK1 and AMPK.
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- Properties
- Applications
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Overview
ULK1 Rabbit mAb
ULK1 Rabbit mAb
Catalog Number:
A001550798RED
Mfr. No.:
RDSA67395
Price:
$470
Size:
100μL
Quantity:
Add to Cart:
.