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UBA3 Rabbit mAb

UBA3 Rabbit mAb

Catalog Number:

A001551457RED

Mfr. No.:

RDSA68054

Price:

$470

Size:

100μL

Quantity:

Add to Cart:

Overview
- Please contact us at for specific academic pricing.
  
  Background
  
  Catalytic subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Down-regulates steroid receptor activity. Necessary for cell cycle progression.
Properties
- Host
  
  rabbit
  
  Antibody Type
  
  monoclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  A synthesized peptide derived from human UBA3
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  
  Storage
  
  Store at -20°C. Avoid freeze / thaw cycles.
  
  Antigen
  
  hUba3;NEDD8 activating enzyme E1C;uba3;UBE1C (UniProt:Q8TBC4)
  
  * This product is for Research Use Only.

Applications

Application

WB

Application	Dilutions
WB	1:500-1:2000

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