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Overview
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Troponin I is the flexible conformationally adaptive part of the Troponin complex interacting with both TnC and TnT, as well as with actin in cardiac muscle. cTnI is the only isoform present in the adult heart and it does not switch under pathological conditions and is released following cardomyosyte stress. Along with Troponin T the levels of Troponin I have been shown, using monoclonal antibodies to specific regions to be diagnostic for myocardial infarction and useful in stratification of cardiac disease.
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