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Overview
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The calcium-sensing component of the Troponin complex is troponin C.The structural
C-domain (cCTnC) contains two high affinity calcium-binding sites that are occupied by Ca2+ or Mg2+ under physiologic conditions, creating an open conformation anchored to the rest of the troponin complex.the regulatory N-domain (cNTnC) contains a single low affinity site that is largely unoccupied at resting calcium concentrations. Troponin C can have applications in mixturess of the other Troponin molecules ( I and T) to form stabilised heterodimers and stabilised complexed Troponin.Please contact us at for specific academic pricing.
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