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Overview
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Background
The tumor necrosis factor (TNF) receptor superfamily is composed of several type I integral membrane glycoproteins that exhibit homology in their cystinerich extracellular domains. Members of this family include TNF-RI, TNF-RII and CD40. Ligands for these receptors can be small, secreted proteins, such as TNF, or type II integral membrane proteins, as is the case for the CD40 ligand, CD40L. While the signal transduction mechanism of the TNF receptor superfamily is poorly understood, activation of TNF-R or CD40 have been shown to induce the nuclear translocation of NFκB.
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- Properties
- Applications
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Overview
TRAF4 Rabbit mAb
TRAF4 Rabbit mAb
Catalog Number:
A001548704RED
Mfr. No.:
RDSA65280
Price:
$470
Size:
100μL
Quantity:
Add to Cart:
.