Total p53 Whole Cell Lysate Kit

p53 is a transcription factor whose activity is upregulated following DNA damage. Activation of p53 results in cell cycle arrest until DNA damage is repaired or in the activation of apoptosis if the cellular damage is too great. Mutations in the tumor suppressor p53 are found in nearly half of all human cancers. This kit provides assay-specific components for the quantitative determination of total p53 in human whole cell lysates.

Please note: This product are transitioned to a status of "made-to-order" with a minimum order size of 25 plates. For an order of the 5-plate pack size, the minimum quantity is 5 packs (25 plates). The 1-plate and 20-plate pack sizes have been discontinued.

Please contact us at for specific academic pricing.

Background

T-PLEX assay kits provide a rapid and convenient method for measuring the levels of biomarkers within a single, small-volume sample. The assays are available in both individual and multiplex formats. T-PLEX assay kits are research grade assays that are grouped into tissue culture, ultra-sensitive, whole cell lysate, serum/plasma, and base kits.

· Benefits: Analyzes protein levels from many sample types with a single assay. Improved analytical performance
· Format: Kits
· Multiplex: Compatible panels
· Sample compatibility: Secreted biomarker assays tested with serum, plasma, and cell culture supernatants; Intracellular assays tested with cell lysates