p-Histone H3 (Ser10) Whole Cell Lysate Kit

Histone H3 is one of the five main classes of histones, which are found in the nucleus of eukaryotic cells, and are the main building blocks of chromatin. It has an amino terminal tail and post-translational modification of this tail is involved in chromatin relaxation and transcriptional regulation. Such epigenetic modifications of histones have been shown to play a role in cancer, embryonic stem cell function, and mammalian development. This kit provides assay-specific components for the quantitative determination of phospho-Histone H3 (Ser10) in human, mouse, and rat whole cell lysates.

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Background

T-PLEX assay kits provide a rapid and convenient method for measuring the levels of biomarkers within a single, small-volume sample. The assays are available in both individual and multiplex formats. T-PLEX assay kits are research grade assays that are grouped into tissue culture, ultra-sensitive, whole cell lysate, serum/plasma, and base kits.

· Benefits: Analyzes protein levels from many sample types with a single assay. Improved analytical performance
· Format: Kits
· Multiplex: Compatible panels
· Sample compatibility: Secreted biomarker assays tested with serum, plasma, and cell culture supernatants; Intracellular assays tested with cell lysates