TNFalpha

TNFalpha

Catalog Number:
AN01097763UBP
Mfr. No.:
U1120
Price:
$440
  • Size:
    50 µg
    Quantity:
    Add to Cart:
    Add to Cart
      • Overview

        • TNFalpha (Tumor necrosis factor alpha) is produced by immune and epithelial cells. It plays important roles in regulating inflammation, apoptosis, and immune response. It exerts its function mainly by binding of two cell surface receptors TNFR1 and TNFR2. Treating cells with TNFalpha activates the NFkappaB, MAPK, and death signaling pathways. The recombinant TNFalpha protein consists of the extracellular domain (amino acids 77-233) of full length TNFalpha. It induces apoptosis of various cancer cells at the concentration of 10-100 ng/mL + 1 ug/mL cycloheximide (a protein translation inhibitor). It is generated from GST-TNFalpha (catlog # U1130) by removal of the N-terminal GST tag.

          Please contact us at for specific academic pricing.

      • Properties
        • Protein Name
          TNF; DIF; TNFA; TNFSF2; TNF-alpha
          Source
          Bacterial recombinant
          Formulation
          20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol
          Storage
          Store at -80°C; avoid multiple freeze-thaw cycles
          Concentration
          See tube label
          Molecular Weight
          25.6 kDa
          Sequence
          NCBI RefSeq: NM_000594.3

          * Research Use Only

    Datasheet

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