Name: Tiotropium Bromide
Price: 180.00 USD

- Overview
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    Background
    
    Tiotropium Bromide is a muscarinic acetylcholine receptor (mAChR M) antagonist that blocks the binding of the acetylcholine ligand and subsequent opening of the ligand-gated ion channel. This stops signaling between neurons and leads to muscle relaxation. Tiotropium Bromide is a long-acting, 24 hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease. Tiotropium Bromide improves symptoms of chronic obstructive pulmonary disease complicated by chronic heart failure.
- Properties
  - Categories
    
    MAChR M antagonist
    
    Alternative Name
    
    Tiopropium; (1R,2R,4S,5S,7s)-7-(2-hydroxy-2,2-di(thiophen-2-yl)acetoxy)-9,9-dimethyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-9-ium bromide
    
    CAS Number
    
    136310-93-5
    
    Molecular Formula
    
    C19H22BrNO4S2
    
    Molecular Weight
    
    472.42
    
    Appearance
    
    A solid
    
    Purity
    
    99.39%
    
    Solubility
    
    ≥23.62 mg/mL in DMSO; insoluble in EtOH; ≥33.07 mg/mL in H2O with ultrasonic
    
    Storage
    
    Store at -20°C
    
    SMILES
    
    O=C(C(C1=C([H])C([H])=C([H])S1)(C2=C([H])C([H])=C([H])S2)O[H])O[[email protected]@]3([H])C([H])([H])[[email protected]]4([H])[N+](C([H])([H])[H])(C([H])([H])[H])[[email protected]@](C3([H])[H])([H])[[email protected]@]5([H])O[[email protected]@]45[H].[Br-]
    
    * For Research Use Only