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Overview
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Background
Thrombomodulin (TM), also called CD141, is a type I membrane receptor that is specific to endothelial cells. TM has a cysteine-rich extracellular domain with six EGF-like regions. It forms a complex with Thrombin, which activates Protein C to generate activated Protein C (APC), an anticoagulant enzyme. APC together with Protein S inhibits coagulation by inactivating Factors Va and VIIIa. Deletion of the TM gene results in embryonic lethality in mice.
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- Properties
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Overview
Thrombomodulin Rabbit mAb
Thrombomodulin Rabbit mAb
Catalog Number:
A001550026RED
Mfr. No.:
RDSA66624
Price:
$470
Size:
100μL
Quantity:
Add to Cart: