Thiabendazole

- Overview
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    Background
    
    Thiabendazole is a benzimidazole compound that acts as a fungicide and is reported to have aneugenic effects. Rat hepatocyte studies suggest that Thiabendazole mediates the induction of CYP1A1 and anuran Xenopus laevis studies demonstrate its ability to elevate the mRNA expression of hsp70 and IL-1β. Other studies indicate that Thiabendazole acts as a time dependent inhibitor of CYP1A2.
- Properties
  - Categories
    
    Fungicide
    
    Alternative Name
    
    4-(1H-benzimidazol-2-yl)-1,3-thiazole
    
    CAS Number
    
    148-79-8
    
    Molecular Formula
    
    C10H7N3S
    
    Molecular Weight
    
    201.25
    
    Appearance
    
    A solid
    
    Purity
    
    99.83%
    
    Solubility
    
    insoluble in H2O; insoluble in EtOH; ≥8.7 mg/mL in DMSO
    
    Storage
    
    Store at -20°C
    
    SMILES
    
    C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3
    
    * For Research Use Only