TGF-beta1, human recombinant protein (CHO cells)

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Background

Transforming Growth Factor-β1 (TGF-β1) is a pleiotropic cytokine mainly produced by platelets and bone, and regulates cell proliferation, growth, differentiation and motility. TGF-β1 is involved in embryogenesis, tissue remodeling, wound healing, hematopoiesis and endothelial differentiation.
The human TGF-β1 cDNA encodes a 390 aa dimeric inactive precursor protein, which is cleaved to an active dimer of 112 residues disulphide-linked peptides. Recombinant human TGF-β1 is a 25.0 kDa protein containing two identical 112 amino acid polypeptide chains linked by a single disulfide bond.