Tetra(-amido-dPEG®₁₁-MAL)pentaerythritol

Tetra(-amido-dPEG®11-MAL)pentaerythritol, product number 11435, is a maleimide-functionalized click chemistry reagent designed to crosslink up to four molecules via a thiol-maleimide reaction. Built around a pentaerythritol core, each arm of this four-branched molecule consists of a single molecular weight, discrete polyethylene glycol (dPEG®) spacer functionalized with a maleimidopropyl group. Each of the four equal-length dPEG®11 arms are from the pentaerythritol core to the reactive site on the maleimide. Applications for this product include crosslinking of proteins, peptides, or small molecules containing free sulfhydryl groups and dendrimer construction with thiol-functionalized branched compounds.

Traditional polyethylene glycol (PEG) is a disperse polymer. Any given size PEG consists of a mixture of different PEG chain lengths, each with a different molecular weight. The stated size of a traditional PEG is an average molecular weight for that mixture. By contrast, our dPEG® products are not disperse polymers. Each dPEG® product contains a single molecular weight of PEG with a discrete chain length, hence the dPEG® name.

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