Name: Terrecyclic Acid
Price: 364.00 USD

- Overview
  - Terrecyclic acid is a tricyclic sesquiterpene antibiotic produced by Aspergillus terreus, first reported by researchers at the Universities of Osaka and Tokyo in 1982. Terrecyclic acid A had a wide antimicrobial spectrum of rather weak activities against gram-positive bacteria, yeasts and fungi, and shows antitumor activity against lymphocytic leukemia P388.
    
    Terrecyclic acid induces the heat shock protein response and affects oxidative and inflammatory cellular stress response pathways in tumor cells that promote survival. Terrecyclic Acid A is shown to increase reactive oxygen species (ROS) in 3LL cells, as well as, inhibit cytokine-induced NF-kappaB transcriptional activity.
    
    Terrecyclic acid is soluble in ethanol, methanol, DMF and DMSO.
    
    Please contact us at for specific academic pricing.
    
    Background
    
    No studies of the mode of action of terrecyclic acid have been published.
- Properties
  - CAS Number
    
    83058-94-0
    
    Molecular Formula
    
    C15H20O3
    
    Molecular Weight
    
    248.3
    
    Appearance
    
    Light tan residue
    
    Storage
    
    -20°C
    
    * For research use only
- Applications
  - Application Description
    
    Spectrum: Terrecyclic acid A had a wide antimicrobial spectrum of rather weak activities against gram-positive bacteria, yeasts and fungi, and shows antitumor activity against lymphocytic leukemia P388.
    Cancer Applications: Terrecyclic acid induces the heat shock protein response and affects oxidative and inflammatory cellular stress response pathways in tumor cells that promote survival. Terrecyclic Acid A is shown to increase reactive oxygen species (ROS) in 3LL cells, as well as, inhibit cytokine-induced NF-kappaB transcriptional activity.