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Teniposide

Teniposide

Catalog Number:
L002369599APE
Mfr. No.:
APE-A8532
Price:
$204
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      • Overview

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          Background

          Teniposide is a glycoside-derivative of podophyllotoxin. Has cytostatic effect. Inhibits topoisomerase II while induces apoptosis.

      • Properties
        • Alternative Name
          (5S,5aR,8aR,9R)-5-[[(2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-thiophen-2-yl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-6-yl]oxy]-9-(4-hydroxy-3,5-dimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[6,5-f][1,3]benzodioxol-8-one
          CAS Number
          29767-20-2
          Molecular Formula
          C32H32O13S
          Molecular Weight
          656.7
          Appearance
          A solid
          Purity
          98.00%
          Solubility
          ≥23.65 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
          Storage
          Store at -20°C

          * For Research Use Only

      • Reference

        • 1. Wang Z, Chen J, et al. "cGAS/STING axis mediates a topoisomerase II inhibitor-induced tumor immunogenicity." J Clin Invest. 2019 Aug 13;130:4850-4862. PMID:31408442

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