Telmisattan

- Overview
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    Background
    
    Telmisartan (INN) is an angiotensin II receptor antagonist (angiotensin receptor blocker, ARB) used in the management of hypertension. It is marketed under the trade name Micardis (by Boehringer Ingelheim), among others.
- Properties
  - Categories
    
    Angiotensin II receptor antagonist
    
    Alternative Name
    
    2-[4-[[4-methyl-6-(1-methylbenzimidazol-2-yl)-2-propylbenzimidazol-1-yl]methyl]phenyl]benzoic acid
    
    CAS Number
    
    144701-48-4
    
    Molecular Formula
    
    C33H30N4O2
    
    Molecular Weight
    
    514.62
    
    Appearance
    
    A solid
    
    Purity
    
    99.92%
    
    Solubility
    
    insoluble in H2O; insoluble in EtOH; ≥9.6 mg/mL in DMSO with gentle warming
    
    Storage
    
    Store at -20°C
    
    SMILES
    
    CCCC1=NC2=C(C=C(C=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C(=O)O)C5=NC6=CC=CC=C6N5C)C
    
    * For Research Use Only
- Reference
  - 1. Jia-jia Xu, Run-jing Li, et al. "Loganin Inhibits Angiotensin II–Induced Cardiac Hypertrophy Through the JAK2/STAT3 and NF-κB Signaling Pathways." Front Pharmacol. 2021 Jun 14;12:678886. PMID:34194329