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Overview
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Calculated MW: 28-42 kDa/53-54 kDa
Observed MW: 53 kDaPlease contact us at for specific academic pricing.
Background
The protein encoded by this gene is a transcriptional activator that plays an important role in lymphocyte differentiation. This gene is expressed predominantly in T-cells. The encoded protein can bind an enhancer element and activate the CD3E gene, and it also may repress the CTNNB1 and TCF7L2 genes through a feedback mechanism. Several transcript variants encoding different isoforms have been found for this gene.
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