Login / Register
0

tatM2NX

tatM2NX

Catalog Number:
P004516719LIF
Mfr. No.:
PEPTIDE-TP-010
Price:
$397
  • Size:
    1mg
    Quantity:
    Add to Cart:
    Add to Cart
      • Overview

        • Cell permeable TRPM2 antagonist.
          tatM2NX is a peptide generated by fusing part of the C-terminus of transient receptor potential melastin 2 (TRPM2) channels, corresponding more than 90% with the Nudix domain (M2NX), with the tat inducer of HIV. tatM2NX is a TRPM2 antagonist which prevents ligand binding and TRPM2 activation, and inhibits over 90% of human TRPM2 channel currents at concentrations as low as 2 μM. tatM2NX is an antagonist with an IC50 of 396 nM and is neuroprotective in animal models of focal and global ischemia.

          Please contact us for availability.

          Please contact us at for specific academic pricing.

      • Properties
        • Categories
          Cell Penetrating Peptides
          Molecular Formula
          C190H323N71O45 S
          Molecular Weight
          4354.17
          Appearance
          Freeze dried solid
          Purity
          >95% by HPLC
          Solubility
          Soluble in water
          Other Properties
          Sequence: H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Gly-Ser-Arg-Glu-Pro-Gly-Glu-Met-Leu-Pro-Arg-Lys-Leu-Lys-Arg-Val-Leu-Arg-Gln-Glu-Phe-Trp-Val-OH,YGRKKRRQRRRGSREPGEMLPRKLKRVLRQEFWV
          Storage
          Store dry, frozen and in the dark

          * Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

    We Also Recommend

    5-FAM-LPETGG

    5-FAM-LPETGG

    $298

    Ac-DEVD-AMC

    Ac-DEVD-AMC

    $190

    Transportan

    Transportan

    $381

    Note: If you don't receive our verification email, do the following:

    Products
    Amerigo Scientific
    Support
    Contact Us
    Copyright © Amerigo Scientific. All rights reserved.