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Tamibarotene

Tamibarotene

Catalog Number:

L002368891APE

Mfr. No.:

APE-A3856

Price:

$188

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- Overview
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    Background
    
    Tamibarotene, Retinoic acid receptor α (RARα) agonist that induces differentiation (ED50 = 0.79 nM) and apoptosis of HL-60 cells in vitro. Tamibarotene exhibits antiproliferative effects against a variety of human tumor cells lines (mean values of 35, 40 and 60% growth inhibition at 0.1, 1 and 10 μM respectively) and displays anticancer activity against acute promyelocytic leukemia in vivo.
- Properties
  - Categories
    
    RARα agonist
    
    Alternative Name
    
    Am80;Am 80;Am-80; 4-[(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)carbamoyl]benzoic acid
    
    CAS Number
    
    94497-51-5
    
    Molecular Formula
    
    C22H25NO3
    
    Molecular Weight
    
    351.44
    
    Appearance
    
    A solid
    
    Purity
    
    98.41%
    
    Solubility
    
    insoluble in H2O; ≥13.35 mg/mL in DMSO; ≥52.5 mg/mL in EtOH with ultrasonic
    
    Storage
    
    Store at -20°C
    
    SMILES
    
    CC1(CCC(C2=C1C=CC(=C2)NC(=O)C3=CC=C(C=C3)C(=O)O)(C)C)C
    
    * For Research Use Only

Documents

COA (Certificate Of Analysis)

NMR (Nuclear Magnetic Resonance)

MSDS (Material Safety Data Sheet)

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