Name: SV106 Delivery™ Human CD8 T cell targeted
Price: 959.00 USD

- Overview
  - A biotechnology company located in the Greater Boston area specializes in the development of advanced lipid nanoparticle (LNP) delivery systems and self-amplifying mRNA (samRNA) platforms. Leveraging a proprietary library of more than one million molecular structures, over 60,000 ionizable lipids have been synthesized and screened using high-throughput technologies. To accelerate progress in the mRNA research community, a series of ready-to-use mouse/human T cell and CD8 T cell specific delivery LNP kits have been launched for research use only for proof-of-concept and screening mRNA constructs ex vivo (in mouse splenic cells, or in human PBMC cells), and in vivo (mouse or humanized mouse).
    
    Please contact us at for specific academic pricing.
- Properties
  - Formulation
    
    For Human CD8 T Cells Delivery of 36 μg mRNA:
    3 x 300μL Lipid Mixture, 1 x 1.5mL Formulation Buffer, 1 x 3mg Reagent A, 1 x 400μL Reagent B-6
    
    For Human CD8 T Cell Delivery of 120 μg mRNA:
    5 x 600μL Lipid Mixture, 2 x 2ml Formulation Buffer, 2 x 3mg Reagent A, 2 x 600μl Reagent B-6
    
    Other Properties
    
    Cell-type specificity: Enabling targeted delivery to human CD8 T cells with exceptional selectivity.
    
    EE (%): 98.7±0.8
    Size (nm): 95.4±1.4
    PDI: 0.15±0.02
    The kits exhibit excellent encapsulation efficiency, generate nanoparticles with a uniform average size of approximately 100 nm, and maintain a low polydispersity index (PDI).
    
    Storage
    
    Lipid Mixture: -80°C
    Formulation Buffer: Room Temperature
    Reagent A: -80°C
    Reagent B-6: 4°C
    
    * For research use only.
- Applications
  - Application Description
    
    For Human CD8 T Cells Delivery of mRNA

Stability of human CD8 T cell targeted LNP-mRNA generated by SV106 Delivery™ Kits.

The SV106 Delivery™ kit demonstrated robust transfection efficiency and cell-type specificity in human PBMC cells.

SV106 Delivery™ Human CD8 T cell targeted

SV106 Delivery™ Human CD8 T cell targeted

Stability of human CD8 T cell targeted LNP-mRNA generated by SV106 Delivery™ Kits.

The SV106 Delivery™ kit demonstrated robust transfection efficiency and cell-type specificity in human PBMC cells.

SV106 Delivery™ Human CD8 T cell targeted

SV106 Delivery™ Human CD8 T cell targeted

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