Suspension Minipig (Gottingen) Hepatocytes, Male

Suspension hepatocytes are non-adherent liver cells used primarily for short-term metabolic and toxicity studies. They retain enzymatic activity but do not attach to culture plates, making them useful for rapid assessments.

Key Characteristics:
• Non-adherent, maintained in a suspension state
• Ideal for short-term drug metabolism assays
• Provide reliable phase I and phase II enzyme activity data

Applications in Drug Testing:
• Short-term drug metabolism studies: Measuring drug clearance rates.
• High-throughput screening (HTS): Rapidly testing multiple compounds for metabolic stability.
• Reaction phenotyping: Identifying enzyme pathways involved in drug metabolism.
• Drug-drug interaction studies: Evaluating competitive metabolism and enzyme inhibition potential.

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