Sulfo-NHS-SS-11-Biotin

Sulfo-NHS-SS-11-Biotin

Catalog Number:
FC01365120APE
Mfr. No.:
APE-A8015
Price:
$252
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      • Overview
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          Background

          Sulfo-NHS-SS-11-biotin is a long-chain cleavable amine-reactive biotinylation reagent. The presence of the negatively charged sulfonate group in the chemical structure of sulfo-NHS-SS-11-biotin makes it a water-soluble biotinylation reagent that can be directly added to aqueous reactions without prior dissolution of organic solvents. Although no prior dissolution is required, an aqueous stock solution of sulfo-NHS-SS-11-biotin must be prepared rapidly and used immediately in case of the occurrence of hydrolysis of the active ester. Sulfo-NHS-SS-11-biotin has been used to react with amine-containing proteins and other molecules forming a complex which further interacts with avidin or streptavidin probes and to purify targeted molecules using affinity chromatography on a column of immobilized avidin or streptavidin.

      • Properties
        • Categories
          Amine-reactive biotinylation reagent, mid-length
          Alternative Name
          sodium 2,5-dioxo-1-((3-((3-oxo-3-((2-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)ethyl)amino)propyl)disulfanyl)propanoyl)oxy)pyrrolidine-3-sulfonate
          Molecular Formula
          C22H32N5NaO10S4
          Molecular Weight
          677.77
          Appearance
          A solid
          Purity
          98.00%
          Solubility
          insoluble in EtOH; ≥48.9 mg/mL in H2O; ≥49.2 mg/mL in DMSO
          Storage
          Store at -20°C
          SMILES
          O=C1N[[email protected]]2([H])[[email protected]]([[email protected]](CCCCC(NCCNC(CCSSCCC(ON3C(CC(S(=O)(O[Na])=O)C3=O)=O)=O)=O)=O)SC2)([H])N1

          * For Research Use Only

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