Name: NHS-SS-11-Biotin
Price: 260.00 USD

- Overview
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    Background
    
    NHS-SS-11-biotin is a long-chain cleavable amine-reactive biotinylation reagent that has a spacer arm of 24.3 A in length due to the existence of a cross-bridge within its chemical structure. The long spacer arm creates an increased length between a covalently modified molecule and the bicyclic biotin rings that greatly enhances the ability of the molecule to bind to avidin or streptavidin probes. The NHS ester group of NHS-SS-11-biotin reacts with the amine groups of proteins and other molecule forming an amide bond and releasing of sulfo-NHS. NHS-SS-11-Biotin is a water-insoluble molecule that requires the dissolution of organic solvents prior to be added to aqueous reactions.
- Properties
  - Categories
    
    Amine-reactive biotinylation reagent, mid-length
    
    Alternative Name
    
    2,5-dioxopyrrolidin-1-yl 3-((3-oxo-3-((2-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)ethyl)amino)propyl)disulfanyl)propanoate
    
    CAS Number
    
    142439-92-7
    
    Molecular Formula
    
    C22H33N5O7S3
    
    Molecular Weight
    
    575.72
    
    Appearance
    
    A solid
    
    Purity
    
    98.00%
    
    Solubility
    
    insoluble in H2O; insoluble in EtOH; ≥16.83 mg/mL in DMSO
    
    Storage
    
    Store at -20°C
    
    SMILES
    
    O=C1N[[email protected]]2([H])[[email protected]]([[email protected]](CCCCC(NCCNC(CCSSCCC(ON3C(CCC3=O)=O)=O)=O)=O)SC2)([H])N1
    
    * For Research Use Only