Sulfapyridine, USP

- Overview
  - Sulfapyridine, USP is a first generation sulfonamide discovered in 1937 by L Whitby at May & Baker, so the compound was named M&B693. Sulfapyridine has also been found to have anti-inflammatory effects and can be used in immunodeficiency studies. It can also be used in oxygen radical absorbance capacity (ORAC) where it scavenges peroxyl radicals. It is practically insoluble in water (0.29 mg/ml) and water solubility is significantly pH dependent. Formulations with sodium salt have a similar potency and improved water solubility.
    
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    Background
    
    Sulfapyridine inhibits folic acid synthesis by acting as a competitive inhibitor of dihydropteroate synthetase, an enzyme found in the folic acid synthesis pathway.
- Properties
  - CAS Number
    
    144-83-2
    
    Molecular Formula
    
    C11H11N3O2S
    
    Molecular Weight
    
    249.29
    
    Solubility
    
    Practically insoluble in water (0.29 mg/ml)
    
    Storage
    
    2-8°C
    
    * For research use only
- Applications
  - Application Description
    
    Spectrum: Sulfapyridine has broad-spectrum activity
    
    Microbiology Applications: Sulfapyridine can be used to study inflammation.