Name: SU 5416
Price: Inquiry

- Overview
  - Please contact us at for specific academic pricing.
- Properties
  - Categories
    
    Enzyme Modulators
    
    Alternative Name
    
    1,3Dihydro-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-2H-indol-2-one
    
    CAS Number
    
    204005-46-9
    
    Molecular Formula
    
    C15H14N2O
    
    MDL Number
    
    MFCD09763655
    
    Note
    
    There is no hazardous surcharge associated with this product.
    There is no special packaging charge associated with this product.
    
    * For research use only. Not for human or veterinary use
- Reference
  - Fong et al (1999). SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and growth of multiple tumor types. Cancer Research, 59(1):99-106.
    Smolich et al (2001). The antiangiogenic protein kinase inhibitors SU5416 and SU6668 inhibit the SCF receptor (c-kit) in a human myeloid leukemia cell line and in acute myeloid leukemia blasts.
    Arora and Scholar (2005). Role of tyrosine kinase inhibitors in cancer therapy. Journal of Pharmacology and Experimental Therapeutics, 315(3):971-9. Blood, 97(5):1413-21.