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Overview
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Steffimycin B is an anthracycline metabolite isolated from a Streptomyces sp. with antibacterial and antineoplastic properties. Crystallographic studies of binding to DNA suggest that it has a higher CpG base sequence specificity over the TpA step, similar to that of daunorubicin and nogalamycin. A close analogue was shown to be active against ras oncogene-expressed cells.
Steffimycin B is soluble in ethanol, methanol, DMF and DMSO.Please contact us at for specific academic pricing.
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- Properties
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Overview