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Overview
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Stearoyl coenzyme A (Stearoyl-CoA) is a saturated fatty acid metabolite which plays a key role in polyunsaturated fatty acid synthesis and the PPAR signaling pathway. Stearoyl-CoA is a primary substrate for stearoyl-CoA desaturase, an enzyme that converts it into oleoyl-CoA—a vital step in the production of monounsaturated fatty acids. This conversion is essential for maintaining lipid homeostasis, influencing membrane fluidity, and regulating metabolic signaling pathways (Paton & Ntambi, 2009; Zeng et al., 2023).
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