Name: ssK36
Price: 298.00 USD

- Overview
  - SET domain containing protein 2 (SETD2) super substrate.
    ssK36, or ssK36 (29-43), is a SET-domain containing protein 2 (SETD2) super substrate. SETD2, also called KMT3A, was first identified as huntingtin interacting protein 1 (HYPB, HIP-1) and can add up to three methyl groups to K36 of histone H39 (H3K36). ssK36 (29-43 has been derived from the currently used SETD2 substrate peptide H3K36 (29-43) but is methylated about 290-fold faster, making it a super substrate. The increased methylation of ssK36 is due to an increase in the rate of catalysis and only to a smaller degree to improved binding.
    
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- Properties
  - Categories
    
    Substrate Peptides
    
    Alternative Name
    
    ssK36 (29-43)
    
    Molecular Formula
    
    C79H127N29O18
    
    Molecular Weight
    
    1771
    
    Appearance
    
    Freeze dried solid
    
    Purity
    
    >95% by HPLC
    
    Solubility
    
    Soluble in water and physiological buffers
    
    Other Properties
    
    Sequence: H-Ala-Pro-Arg-Phe-Gly-Gly-Val-Lys-Arg-Pro-Asn-Arg-Tyr-Arg-Pro-OH,APRFGGVKRPNRYRP
    
    Storage
    
    Store desiccated, frozen and in the dark
    
    * Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

ssK36

ssK36

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