SPDP-dPEG®₃₆-NHS ester

- Overview
  - SPDP-dPEG®36-NHS ester, product number 10867, is an amphiphilic, water-soluble, monodispersed PEGylation reagent that is designed to crosslink amines and free thiols. SPDP (sometimes referred to as orthopyridyl disulfide, or OPSS, in the scientific literature) reacts with sulfhydryl groups to form disulfide bonds. The N-hydroxysuccinimidyl (NHS) ester reacts with free amines to form amide bonds.
    
    PEGylation with Quanta BioDesign's dPEG® Products
    Oursingle molecular weight, discrete chain length PEGylation reagents are quite different from traditional PEGylation reagents. Our products are not dispersed polymers, nor are they purified from polymeric mixtures. Instead, we synthesize all of our products from high-purity starting materials and maintain discrete chain lengths and single molecular weights throughout the entire synthetic process.
    
    Please contact us at for specific academic pricing.
- Properties
  - Categories
    
    Crosslinking Reagents
    
    CAS Number
    
    924280-65-9
    
    Molecular Weight
    
    1969.33; single compound
    
    Purity
    
    > 98%
    
    Other Properties
    
    dPEG® Spacer is 115 atoms and 137.8 Å
    
    * For Research Use Only
- Reference
  - Greg T. Hermanson, Bioconjugate Techniques, 2nd Edition, Elsevier Inc., Burlington, MA 01803, April, 2008 (ISBN-13: 978-0-12-370501-3; ISBN-10: 0-12-370501-0); See pp. 276-335 for general description and use of heterobifunctional crosslinkers, and the specific sample protocol for SPDP and LC-SPDP on pp. 286-288. See Greg’s extensive index on pp. 1192-1193 for references to a number and range of applications and their respective protocols.

MSDS

SPDP-dPEG®₃₆-NHS ester

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