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Overview
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Somatostatin and its related peptide cortistatin exert multiple biological actions on normal and tumoral tissue targets by interacting with somatostatin receptors (SSTs). It is one of the SSTs, which is a multi-pass membrane protein and belongs to the GPCR 1 family. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase and different regions of this receptor molecule are required for the activation of different signaling pathways. A mutation in the gene results in somatostatin analog resistance. Alternatively spliced transcript variants have been identified in this gene.
Includes:
ExpressMAX™ GPCR ORF Clones (Cat. No. – B)
– Vector as transformed Bacteria in stab culture or a Glycerol Stock format.
Mammalian Transfection Kits (Cat. No. – PLUS)
– 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL).
– 0. 2 mL CANFAST™ Transfection Reagent.Please contact us at for specific academic pricing.
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- Properties
- Applications
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Overview