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Sitaxsentan sodium

Sitaxsentan sodium

Catalog Number:
L002234520BIO
Mfr. No.:
FS27842
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      • Overview

        • Endothelin A receptor antagonist

          Please contact us at for specific academic pricing.

      • Properties
        • Categories
          Ligands of GPCRs
          Alternative Name
          Sodium (4-chloro-3-methyl-1,2-oxazol-5-yl)-[2-[2-(6-methyl-1,3-benzodioxol-5-yl)acetyl]thiophen-3-yl]sulfonylazanide
          CAS Number
          210421-74-2
          Molecular Formula
          C18H14ClN2NaO6S2
          Molecular Weight
          476.89 g/mol
          MDL Number
          MFCD11040990
          Note
          There is no hazardous surcharge associated with this product.
          There is no special packaging charge associated with this product.

          * For research use only. Not for human or veterinary use

      • Reference

        • Wu et al (1997). Discovery of TBC11251, a Potent, Long Acting, Orally Active Endothelin Receptor-A Selective Antagonist1. Journal of Medicinal Chemistry, 40(11) 1690-1697.
          Horn et al (2004). Sitaxsentan, a selective endothelin-A receptor antagonist for the treatment of pulmonary arterial hypertension. Expert Opinion on Investigational Drugs.13(11):1483-92.
          Langleben et al (2004). Sustained symptomatic, functional, and hemodynamic benefit with the selective endothelin-A receptor antagonist, sitaxsentan, in patients with pulmonary arterial hypertension: a 1-year follow-up study. Chest. 126(4):1377-81.

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