Alprostadil

- Overview
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    Background
    
    Prostaglandin E1 (Alprostadil) is a prostaglandin, which is used in the treatment of erectile dysfunction and has vasodilatory properties.
- Properties
  - Categories
    
    vasodilator
    
    Alternative Name
    
    7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]heptanoic acid
    
    CAS Number
    
    745-65-3
    
    Molecular Formula
    
    C20H34O5
    
    Molecular Weight
    
    354.48
    
    Appearance
    
    A solid
    
    Purity
    
    99.99%
    
    Solubility
    
    insoluble in H2O; ≥13.4 mg/mL in DMSO; ≥47.1 mg/mL in EtOH
    
    Storage
    
    Store at -20°C
    
    SMILES
    
    CCCCCC(C=CC1C(CC(=O)C1CCCCCCC(=O)O)O)O
    
    * For Research Use Only
- Reference
  - 1. Fei S, Li W, et al. "Protective Effect of Alprostadil on Acute Pancreatitis in Rats via Inhibiting Janus Kinase 2 (JAK2)/STAT3 Signal Transduction Pathway." Med Sci Monit. 2019 Oct 13;25:7694-7701. PMID:31606729