SII Preclinical In Vivo Optical Imaging System

Bioluminescence, Fluorescence, Cerenkov and Brightfield Imaging
Optional X-ray and Quantitative 3D Imaging and Analysis
Unrivaled Sensitivity and Minimum Detectable Radiance
Cutting edge LED Fluorescence Illumination
Industry leading FOV and High Throughput

Product Principles
Bioluminescence Imaging (BLI): BLI is a technology that uses light emitted by enzyme-catalyzed reactions to report activity at the molecular level, which does not need the excitation light source, the background is low and the signal-to-noise ratio is high.
Fluorescence Imaging (FLI): FLI is the visualization of fluorescent dyes or proteins as labels for molecular processes or structures, which needs the excitation light source, the background is relatively high and the signal-to-noise ratio is relatively low.
Cherenkov luminescence imaging (CLI): CLI is an emerging imaging modality, similar to bioluminescence imaging, that captures visible photons emitted by Cherenkov radiation. It basically is the optical imaging of radiotracers that emit charged particles traveling faster than the phase velocity of light in that particular medium.
X-ray Imaging: A beam of X-rays is produced by an X-ray generator and is projected toward the object. A certain amount of the X-rays or other radiation is absorbed by the object, dependent on the object's density and structural composition. The X-rays that pass through the object are captured behind the object by a detector.
Engineered with superior optics and industry leading technology, Spectral Instruments Imaging provides unrivaled sensitivity for bioluminescence, fluorescence, and X-ray in vivo imaging. Intelligently designed around the needs of animal scientists, all Spectral Instrument Imaging systems include a robust build, patented LED illumination source, custom filter options, -90°C cooled camera, and absolute calibration. Lago and Ami systems enable high throughput imaging and field upgradable X-ray.

Product Characteristics
· -90°C Absolute Cooled Camera with Grade One Plus CCD
Ultra cold for maximum sensitivity
· Unprecedented Detection
Previously unattained sensitivity for Bioluminescence and Fluorescence (BLI/FLI)
· Unrivaled Sensitivity
Minimum Detectable Radiance is 45 photons/sec/cm^2/sr
· LED Fluorescence Illumination
Cutting edge patented LED based illumination
· 14 Wavelengths/20 Filters
Be prepared for any fluorophore at any time. No need to change filters.
· Robust Design
Built to perform for the crucial demands of imaging cores and CRO's
· Absolute Calibration
Ensures quantifiable data
· Field Upgradable
Lago units are field upgradable to include X-ray, Access Ports and Quantitative 3D Optical Imaging, with minimal downtime.
· 10 Mouse Capacity (BLI/FLI/X-ray)
Industry leading 25cm x 25cm field of view
· Software is 100% License Free
Available for PC & Mac users

Please contact us at for specific academic pricing.