Fluorescence In Vivo Endomicroscope 2nd generation

Fluorescence In Vivo Endomicroscope 2nd generation

Catalog Number:
LARE506021SIN
Mfr. No.:
SIN240041AM
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    EA
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      • Overview
        • The hand-held OptiScan FIVE2 system is the most advanced miniaturised confocal endomicroscope in the world.The FIVE2 enables you to push the boundaries of your research with maximum flexibility, viewing tissue at any angle with sub-micron resolution.
          Product Principle
          Optiscan technology is easy to use. Following application of a fluorescent dye, simply touch the probe against the tissue of interest and an image will be displayed on the screen in front of you.
          A laser light passes through an optical fibre to a hand-held probe. Optics in the probe focus the laser to a diffraction limited spot in the tissue. Fluorescence is excited at this spot and the fluorescent light is captured into the optical fibre and passed to a detector. An image is generated by scanning the focussed spot through an image plane, then compiling the point intensity measurements. The image plane can be translated in depth, allowing generation of 3D image stacks.

          Product Features
          · Slide-free and biopsy free: users can generate images at the sub-cellular level, in real-time.
          · Viewing live biological systems in-vivo at the cellular level in their entirety:not achievable through other imaging techniques.
          · Non-destructive: image creation is non-destructive to the tissue of interest.
          · Portable: easy to work on live tissues.
          · Image depth variation:unique ability to vary image depth in the Z-Axis:up to 400 microns (tissue dependent).
          · Zero cost image acquisition: just staining cost required.
          · Post-processing versatility: images can be easily post-processed to produce a range of presentations (incl 3D)

          Please contact us at for specific academic pricing.

      • Properties
        • Other Properties
          The flflexible hand-held probe of the FIVE2
          Images can be captured at any angle with sub-micron resolution
          Image resolution is 0.55µm lateral and 5.1µm Axial
          Vary image depth in the Z-Axis: up to 400 microns(tissue dependent)
          Thin optical sections enable reconstruction of 3D tissue structure in remarkable detail
      • Applications
        • Application Description
          Cancer research
          • Tumour development/regression
          • Metastasis
          • Tumour detection/diagnosis
          • Border demarcation
          Tissue regeneration
          • Stem cell research
          • Orthopaedic tissue engineering
          • Scaffold imaging
          • Tissue rejection
          Cell tracking
          • Stem cell research
          • Inflammatory responses
          • Cell-cell & cell-tissue interactions
          Photodynamic Therapy (PDT)
          • Photosensitiser distribution
          • PDT response
          • Lesion detection & identification (PDD)
          Infection & treatment
          • Tissue microflora µbicide response
          Pharmacology
          • Drug delivery & pharmacokinetics
          • Tissue response
          Pathology
          • Acute lung injury & animal models
          • Liver disease models
          • Morphological changes in disease
          Microvascular research
          • Dynamics and structure
          • Angiogenesis/anti-angiogenesis
          • Thrombosis
          Animal models
          • Tissue injury & disease
          Molecular Imaging
          • Receptor labelling
          • Protein expression profiling
          • Transgenic animals (eg GFP/YFP)

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