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Overview
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Background
SB-408124 (SB 408124) is a selective non-peptide orexin OX1 receptor antagonist .(Kb values are 21.7 and 1405 nM for human OX1 and OX2 receptors respectively). SB-408124 (SB 408124) blocks orexin-A induced grooming following oral administration in vivo.
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Overview