Name: SAFB Polyclonal Antibody
Price: 347.00 USD

Overview
- Please contact us at for specific academic pricing.
  
  Background
  
  This gene encodes a DNA-binding protein which has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. The encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes. It is involved in the regulation of heat shock protein 27 transcription, can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis. This gene is arranged head-to-head with a similar gene whose product has the same functions. Multiple transcript variants encoding different isoforms have been found for this gene.
Properties
- Host
  
  rabbit
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  A synthetic peptide of human SAFB (NP_002958.2).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3
  
  Storage
  
  Store at -20°C. Avoid freeze-thaw cycles.
  
  Concentration
  
  1 mg/mL
  
  Antigen
  
  SAFB, HAP, HET, SAB-B1, SAF-B, SAF-B1, SAFB1 (Gene ID:6294; UniProt:Q15424)
  
  * For reference only.

Applications

Application

IF

Application	Dilutions
IF	1:50-1:200

SAFB Polyclonal Antibody

SAFB Polyclonal Antibody

Background

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