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S1H

S1H

Catalog Number:
P004516914LIF
Mfr. No.:
PEPTIDE-CY-010
Price:
$314
  • Size:
    1mg
    Quantity:
    Add to Cart:
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      • Overview

        • Human growth hormone receptor antagonist.
          S1H is a 16-residue peptide designed as a direct sequence mimetic of the site 1 mini-helix (residues 36-51) of wild-type human growth hormone (hGH). S1H acts as an inhibitor by blocking the interaction of hGH with the human growth hormone receptor (hGHR). S1H mitigates phosphorylation of STAT5 in cells co-treated with hGH, reducing intracellular STAT5 phosphorylation levels to those of untreated controls. S1H can be used as a chemical tool to study the molecular nature of hGH hGHR interactions.

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          Please contact us at for specific academic pricing.

      • Properties
        • Categories
          Peptides
          Alternative Name
          S1H (36-51)
          Molecular Formula
          C94H141N23O27
          Molecular Weight
          2025.29
          Appearance
          Freeze dried solid
          Purity
          >95% by HPLC
          Solubility
          Soluble in water
          Other Properties
          Sequence: Ac-Tyr-Ile-Pro-Lys-Glu-Gln-Lys-Tyr-Ser-Phe-Leu-Gln-Asn-Pro-Gln-Thr-NH2,Ac-YIPKEQKYSFLQNPQT-NH2
          Modification: N terminal acetyl, C terminal amide
          Storage
          Store dry, frozen and in the dark

          * Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

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