Ruxolitinib phosphate

Ruxolitinib phosphate

Catalog Number:
L002368852APE
Mfr. No.:
APE-A3781
Price:
$188
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      • Overview
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          Background

          INCB018424 (Ruxolitinib) is an orally bioavailable JAK inhibitor .(IC50 values for JAK1, JAK2 and JAK3 are 3, 5 and 332 nM, respectively).INCB018424 is useful for rheumatoid arthritis.

      • Properties
        • Alternative Name
          INCB018424 phosphate;INCB 018424 phosphate;INCB-018424 phosphate;Ruxolitinib; (3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile;phosphoric acid
          CAS Number
          1092939-17-7
          Molecular Formula
          C17H21N6O4P
          Molecular Weight
          404.36
          Appearance
          A solid
          Purity
          99.73%
          Solubility
          ≥20.2 mg/mL in DMSO; ≥6.92 mg/mL in EtOH with gentle warming and ultrasonic; ≥8.03 mg/mL in H2O with gentle warming and ultrasonic
          Storage
          Store at -20°C

          * For Research Use Only

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