Login / Register

0

Rupatadine Fumarate

Rupatadine Fumarate

Catalog Number:

L002370097APE

Mfr. No.:

APE-B1566

Price:

$260

Size:

Quantity:

Add to Cart:

- Overview
  - Please contact us at for specific academic pricing.
    
    Background
    
    Rupatadine is an inhibitor of PAFR and histamine (H1) receptor with Ki of 550 nM and 102 nM, respectively. Phase 2.
- Properties
  - Alternative Name
    
    (E)-but-2-enedioic acid;8-chloro-11-[1-[(5-methylpyridin-3-yl)methyl]piperidin-4-ylidene]-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridine
    
    CAS Number
    
    182349-12-8
    
    Molecular Formula
    
    C26H26ClN3·C4H4O4
    
    Molecular Weight
    
    532.03
    
    Appearance
    
    A solid
    
    Purity
    
    98.00%
    
    Solubility
    
    insoluble in H2O; ≥11.75 mg/mL in DMSO; ≥12.55 mg/mL in EtOH with gentle warming
    
    Storage
    
    Store at -20°C
    
    SMILES
    
    CC1=CC(=CN=C1)CN2CCC(=C3C4=C(CCC5=C3N=CC=C5)C=C(C=C4)Cl)CC2.C(=CC(=O)O)C(=O)O
    
    * For Research Use Only
- Reference
  - 1. Bravo DD, Chernov-Rogan T, et al. "An impedance-based cell contraction assay using human primary smooth muscle cells and fibroblasts." J Pharmacol Toxicol Methods. 2017 Oct 19;89:47-53. PMID:29056519

Note: If you don't receive our verification email, do the following:

Confirm that you entered your email address correctly.
Check if the email is in your spam or junk folder.
Or you may contact us at .