Rosuvastatin

Rosuvastatin

Catalog Number:
L002369827APE
Mfr. No.:
APE-B1123
Price:
$286
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      • Overview

        • Please contact us at for specific academic pricing.

          Background

          Rosuvastatin is a competitive inhibitor of HMG-CoA reductase with IC50 of 11 nM.

      • Properties
        • Alternative Name
          (E,3R,5S)-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-propan-2-ylpyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid
          CAS Number
          287714-41-4
          Molecular Formula
          C22H28FN3O6S
          Molecular Weight
          481.54
          Appearance
          A solid
          Purity
          98.00%
          Solubility
          ≥48.2 mg/mL in DMSO; ≥10.78 mg/mL in H2O with ultrasonic; ≥12.4 mg/mL in EtOH with ultrasonic
          Storage
          Store at -20°C
          SMILES
          CC(C)C1=NC(=NC(=C1C=CC(CC(CC(=O)O)O)O)C2=CC=C(C=C2)F)N(C)S(=O)(=O)C

          * For Research Use Only

      • Reference

        • 1. Jiawei Zhuang, Gangyi Cheng, et al. "Rosuvastatin exerts cardioprotective effect in lipopolysaccharide-mediated injury of cardiomyocytes in an MG53-dependent manner." BMC Cardiovasc Disord. 2022 Feb 23;22(1):69. PMID:35196979

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