Name: RNase R, GMP Grade
Price: 450.00 USD

- Overview
  - Ribonuclease R (RNase R), derived from the Escherichia coli RNR superfamily, is a magnesium ion dependent 3 '- 5' exonuclease that can progressively cut RNA into dinucleotides and trinucleotides from the 3 '- 5' direction. RNase R can digest almost all linear RNAs, but it is difficult to digest circular RNAs, lasso RNAs, and short double-stranded RNAs with less than 7 nucleotides of 3 'end protrudation. RNase R is commonly used in gene expression and can digest linear RNAs to enrich circular RNAs or lasso structured RNAs.
    
    We guarantee the manufacturing and quality control comply with GMP regulation for tracking each and every step of the manufacturing process, including raw material sourcing.
    
    Appearance: Clear and transparent solution
    Visible Particles: Meet the specification
    pH: 7.0-8.0
    Endonuclease Residues: The degradation of substrate was ≤10%
    Exonuclease Residues: The degradation of substrate was ≤10%
    Heavy Metal Residues: ≤10ppm
    Microbial Limit: Total aerobic microbial count ≤1cfu/10ml, total yeasts and molds count≤1cfu/10ml
    Activity Definition: At 37°C, within 10 mins, the amount of enzyme required that will degrade 1µg poly(A) turning to acid-soluble nucleotides is defined as one unit of enzyme activity
    
    Please contact us at for specific academic pricing.
- Properties
  - Purification
    
    Purity ≥95%
    
    Storage
    
    At -20±5°C
    
    Endotoxin
    
    <10EU/ml
    
    Activity
    
    ~20U/μl
    
    * For Research or Manufacturing Use Only, Not for Use in Diagnostic or Therapeutic Procedures.

RNase R, GMP Grade

RNase R, GMP Grade

We Also Recommend

BspQI Restriction Endonuclease, GMP Grade (10U/μl)

E. coli Poly(A) Polymerase, GMP Grade

XbaI Restriction Enzyme, GMP Grade