RNase R (20 U/μL)

Ribonuclease R (RNase R) from E. coli, is a magnesium-dependent 3′→5′ exoribonuclease that can digest all linear RNAs but does not digest lariat or circular RNA structures. Most cellular RNAs will be digested completely by RNase R, with the exception of tRNAs, 5S RNA and intron lariats. RNase R is used for enrichment of circRNAs in biological samples, identification of intronic lariat sequences, identification of exonic circRNAs, studying alternative splicing.

Features
• Guaranteed efficacy and quality with ISO 13485 certification.
• Available in bulk or tailored configurations.
• Effectively breaks down linear RNA, while preserving lariat loops and circular RNAs.
• Selective digestion of linear RNAs enhances the isolation of circular RNAs for protein production or intronic cDNA library construction.
• Offering GMP-Grade RNAse R (14615)

Please contact us at for specific academic pricing.