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Reveromycin A

Reveromycin A

Catalog Number:

M001342129TOK

Mfr. No.:

TOK-R022

Price:

$500

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- Overview
  - Reveromycin A, the dominant analogue of a complex of spiroketals isolated from a Streptomyces sp., is an inhibitor of the mitogenic activity of EGF. Reveromycin A displays antiproliferative behaviour against human cell lines KB and K562, as well as potent antifungal activity. More recently it has been shown to induce apoptosis in osteoclasts thus inhibiting bone resorption.
    
    Reveromycin A is soluble in ethanol, methanol, DMF and DMSO.
    
    Please contact us at for specific academic pricing.
    
    Background
    
    Reveromycin A is a G1 phase cell cycle inhibitor, selectively inhibiting isoleucyl-tRNA synthetase.
- Properties
  - CAS Number
    
    134615-37-5
    
    Molecular Formula
    
    C36H52O11
    
    Molecular Weight
    
    660.8
    
    Appearance
    
    Tan Lyophilisate
    
    Storage
    
    -20°C
    
    * For research use only

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