Recombinant Human TRKC (N-His tag)

Recombinant Human TRKC (N-His tag)

Catalog Number:
E001278587APP
Mfr. No.:
Z500394
Price:
$672
  • Size:
    10 µg
    Quantity:
    Add to Cart:
      • Overview
        • TRKC is a member of the TRK family of tyrosine kinase receptors and is the high affinity catalytic receptor for the neurotrophin NT-3 (neurotrophin-3). TRKC mediates the multiple cellular effects of the NT-3 neurotrophic factor, which includes neuronal differentiation and survival. TRKC has been implicated in insulin signaling pathway through interactions with the MUSK protein receptor and the VEGF receptor. Mutations in the TRKC gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.

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      • Properties
        • Name
          NTRK3, gp145(trkC)
          Source
          Insect cells
          Type
          Recombinant Proteins
          Formulation
          50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
          Storage
          Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
          Molecular Weight
          38.0 kDa
          Class
          Active Kinases

          * For research use only. Not for diagnostic or therapeutic use.

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