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Recombinant Human TRKB (N-GST tag)

Recombinant Human TRKB (N-GST tag)

Catalog Number:
E001278589APP
Mfr. No.:
Z500393
Price:
$672
  • Size:
    10 µg
    Quantity:
    Add to Cart:
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      • Overview

        • TRKB is a member of the neurotrophic tyrosine receptor kinase (NTRK) family. TRKB is the high affinity catalytic receptor for several "neurotrophins", which are small protein growth factors that induce the survival and differentiation of distinct cell populations. TRKB is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through TRKB leads to cell differentiation. Mutations in the TRKB gene have been associated with obesity and mood disorders.

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      • Properties
        • Name
          NTRK2, GP145-TrkB
          Source
          Insect cells
          Type
          Recombinant Proteins
          Formulation
          50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
          Storage
          Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
          Molecular Weight
          67.0 kDa
          Class
          Active Kinases

          * For research use only. Not for diagnostic or therapeutic use.

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