Recombinant Human Transforming Growth Factor Beta Receptor Associated Protein 1

Recombinant Human Transforming Growth Factor Beta Receptor Associated Protein 1

Catalog Number:
P001414287ABE
Mfr. No.:
Abe32-5067
Price:
  • Size:
    10 µg
    Quantity:
    Add to Cart:
      • Overview
        • TGFBRAP1 Human Recombinant produced in E. Coli is a single, non-glycosylated polypeptide chain containing 296 amino acids (601-860 a.a) and having a molecular mass of 33kDa. TGFBRAP1 is fused to a 36 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. TGF-beta receptor-associated protein 1 also knownas TGFBRAP1 takes part in the TGF-beta/activin signaling pathway. TGFBRAP1 isrelated with inactive heteromericTGF-beta and activin receptor complexes, mainly through the typeII receptor, and is released upon activation of signaling. TGFBRAP1 recruits SMAD4 to the vicinity of the receptor complex and smoothes the progress of its interaction with receptor-regulated Smads, such as SMAD2.

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      • Properties
        • Protein Name
          TRAP-1, TRAP1, Transforming growth factor-beta receptor-associatedprotein 1, TGF-beta receptor-associated protein 1.
          Source
          E. coli
          Type
          Recombinant Proteins
          Purification
          Greaterthan 80% as determined by SDS-PAGE.
          Formulation
          TGFBRAP1 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol.
          Storage
          Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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