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Recombinant human TIGIT Protein with C-His tag

Recombinant human TIGIT Protein with C-His tag

Catalog Number:
P001417526ABE
Mfr. No.:
Abe32-17110
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      • Overview

        • The protein has a predicted molecular mass of 13.85 kDa after removal of the signal peptide. The apparent molecular mass of TIGIT-His is approximately 17-25 kDa due to glycosylation. This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.

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      • Properties
        • Protein Name
          TIGIT, VSIG9, VSTM3
          Source
          HEK293 cells
          Type
          Recombinant Proteins
          Purification
          The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
          Formulation
          Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
          Storage
          Store at -80°C for 12 months (Avoid repeated freezing and thawing)

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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